WHAT IS PHMB?
PHMB also known has Polyhexamethylene biguanide, also known as polyhexanide, is a polymerized biguanide compound used as a broad-spectrum antiseptic, disinfectant and preservative.
It has been proven to be effective against wide range of pathogens, including strains of Escherichia coli, Staphylococcus epidermidis, and even Protista Acanthamoeba Castellani.
It has been previously thought to work primarily through microbial membrane disruption, however, more recently it has been reported to also selectively bind and condense bacterial DNA, arresting bacterial cell division.
This mechanical antimicrobial mechanism of action may help explain why PHMB has a low risk for antimicrobial resistance, of which, none has been recorded despite extensive testing since its first synthesis.
WHERE IS PHMB USED?
PHMB is specifically used in several things in our day-to-day life, which we are not aware about, some of the examples are, wound care dressings, contact lens cleaning solutions, perioperative cleansing products and swimming pool cleaners.
it has been a very good alternative to replace chlorine in terms of swimming pool cleaners, since chlorine has its own side effects, whereas on the other hand PHMB has no particular side effect as compared to chlorine.
There are several advantages of using PHMB and the list of them are mentioned below:
- ANTIMICROBIAL PROPERTIES:
- It is a broad-spectrum antimicrobial agent that is effective against bacteria, viruses, fungi, and spores.
- NON-TOXIC:
- PHMB is non-toxic and does not cause irritation to the skin or mucous membranes. It is also noncarcinogenic and does not pose a risk to human health.
- WIDE RANGE OF APPLICATIONS:
- PHMB can be used in variety of applications, including medical devices, wound care, water treatment and food processing.
- LONG-LASTING ACTIVITY:
- PHMB has a long-lasting activity against microorganisms, making it an effective disinfectant and preservative.
- COMPATIBILITY WITH OTHER MATERIALS:
- PHMB is compatible with a wide range of materials, including plastics, metals and rubbers.
- ENVIRNOMENTAL FRIENDLINESS:
- PHMB is environment friendly and biodegradable, making it a preferred choice over other disinfectants that may harm the environment.
- COST-EFFECTIVE:
- PHMB is a cost-effective alternative to other disinfectants due to its long-lasting activity and broad-spectrum antimicrobial activities.
- REDUCED RISK OF RESISTANCE:
- PHMB has low risk of microbial resistance due to its unique mode action, which makes it an effective choice for preventing the spread of antibiotic-resistant bacteria.
PHMB comes under the category of Bacteria static as well as Bacteria seed. PHMB is quietly making waves in the wound care industry, bringing forth a symphony of healing that resonates innovation in the industry.
Unlike traditional treatments PHMB conducts a unique cellular concert, disrupting the harmony of bacteria and fungi, and maintaining a powerful defense against infections.
Its molecular composition is such rare and difficult to master that it strikes a perfect compatibility between efficacy and biocompatibility providing a balanced healing environment for different types of wounds. PHMB’s adaptability is one of the greatest assets, since it can seamlessly integrate into different wound care products.
From dressings that are used on acute wounds, to dressings that are used to treat chronic wounds. PHMB makes sure that each customer receives a unique healing experience. As the medical (wound) care industry continues to grow PHMB is positioned as a prelude to future innovations in wound care.
Various researches have led to the conclusion of its unique potential of combinational therapies and its impact on disruption of the bio film.
treetta products having the composition of PHMB:
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- It contains powerful antimicrobial compounds such as Polyhexanide (PHMB) and an amphoteric betaine surfactant. The combination of PHMB and betaine is considered as an ideal combination for the treatment of wounds.
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- TEBASEPT Gel X is an advanced cleansing hydrogel containing polyhexanide and betaine in optimum viscosity which is used to prevent and disrupt the biofilm formation.
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- TEBASEPT GEL X PLUS is an advanced version of the Wound Gel X, having higher viscosity, PHMB, amphoteric surfactant along with HEC (Hydroxyethyl cellulose), it is mainly for debride wounds.
- TEBAFLEX-PHMB Antimicrobial Dressing
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- TEBAFLEX is a PHMB impregnated Polyurethane foam with a vertical absorption of exudate, wound moisture management, flexibility and antimicrobial activity, which provides an ideal environment for wound healing.
In conclusion PHMB (Polyhexamethylene Biguanide) has emerged as a game changer in the wound industry due to its unique properties and benefits.
It’s broad-spectrum antimicrobial activity against bacteria, viruses, fungi and spores coupled with its non-toxicity and environmental friendliness, make it and ideal choice for wound care applications.
PHMB’s long lasting activity and also its compatibility with various materials also makes it a cost-effective alternative to other disinfectants.
Moreover, its low risk of microbial resistance reduces the risk of antibiotic-resistant bacteria, which is a major concern in the wound care industry.
As the demand for effective wound care products continues to grow, PHMB’s advantages and benefits make it a promising candidate for future research and development in this field.
Its potential to improve patient outcomes and reduce healthcare costs highlights the importance of continued investment in PHMB research and its integration into the wound care products.
As such PHMB’s role in the wound care industry is expected to grow significantly in the coming years, as the healthcare providers seek out innovative solutions to address the challenges of wound care management.